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Immunoproteasome β5i-Selective Dipeptidomimetic Inhibitors
N,C-capped dipeptides belong to a class of noncovalent proteasome inhibitors. Here we report that insertion of a β-amino acid in N,C-capped dipeptides markedly reduces the inhibitory potency against human constitutive proteasome, yet maintains potent inhibitory activity against human immunoproteasom...
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| Udgivet i: | ChemMedChem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5760267/ https://ncbi.nlm.nih.gov/pubmed/27561172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600384 |
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