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Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome
[Image: see text] Selective inhibitors for the human immunoproteasome LMP7 (β5i) subunit over the constitutive proteasome hold promise for the treatment of autoimmune and inflammatory diseases and hematologic malignancies. Here we report that oxathiazolones inhibit the immunoproteasome β5i with up t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027612/ https://ncbi.nlm.nih.gov/pubmed/24900849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400531d |
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