Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice

Constitutive proteasomes (c-20S) are ubiquitously expressed cellular proteases that degrade polyubiquitinated proteins and regulate cell functions. An isoform of proteasome, the immunoproteasome (i-20S), is highly expressed in human T cells, dendritic cells (DCs), and B cells, suggesting that it cou...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Sula Karreci, Esilida, Fan, Hao, Uehara, Mayuko, Mihali, Albana B., Singh, Pradeep K., Kurdi, Ahmed T., Solhjou, Zhabiz, Riella, Leonardo V., Ghobrial, Irene, Laragione, Teresina, Routray, Sujit, Assaker, Jean Pierre, Wang, Rong, Sukenick, George, Shi, Lei, Barrat, Franck J., Nathan, Carl F., Lin, Gang, Azzi, Jamil
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2016
נושאים:
PNAS Plus
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206568/
https://ncbi.nlm.nih.gov/pubmed/27956634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618548114
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