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Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival

The targeted delivery of therapeutic drugs to lymph nodes (LNs) provides an unprecedented opportunity to improve the outcomes of transplantation and immune-mediated diseases. The high endothelial venule is a specialized segment of LN vasculature that uniquely expresses peripheral node addressin (PNA...

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Pubblicato in:J Clin Invest
Autori principali: Bahmani, Baharak, Uehara, Mayuko, Jiang, Liwei, Ordikhani, Farideh, Banouni, Naima, Ichimura, Takaharu, Solhjou, Zhabiz, Furtmüller, Georg J., Brandacher, Gerald, Alvarez, David, von Andrian, Ulrich H., Uchimura, Kenji, Xu, Qiaobing, Vohra, Ishaan, Yilmam, Osman A., Haik, Yousef, Azzi, Jamil, Kasinath, Vivek, Bromberg, Jonathan S., McGrath, Martina M., Abdi, Reza
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205374/
https://ncbi.nlm.nih.gov/pubmed/30277476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120923
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