The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion

Primary and secondary hypertension are major risk factors for cardiovascular disease, the leading cause of death worldwide. Elevated secretion of aldosterone resulting from primary aldosteronism (PA) is a key driver of secondary hypertension. Here, we report an unexpected role for the ubiquitin liga...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Scortegagna, Marzia, Berthon, Annabel, Settas, Nikolaos, Giannakou, Andreas, Garcia, Guillermina, Li, Jian-Liang, James, Brian, Liddington, Robert C., Vilches-Moure, José G., Stratakis, Constantine A., Ronai, Ze’ev A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752272/
https://ncbi.nlm.nih.gov/pubmed/29212953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97128
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados