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Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2
The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). Yet, it is not known how UPR-signaling coordinates adaptation versus cell death. Previous studies suggested that signaling through PERK/ATF4 is required for cell...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014425/ https://ncbi.nlm.nih.gov/pubmed/24809345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004348 |
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