Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2

The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). Yet, it is not known how UPR-signaling coordinates adaptation versus cell death. Previous studies suggested that signaling through PERK/ATF4 is required for cell...

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Bibliografiske detaljer
Main Authors: Scortegagna, Marzia, Kim, Hyungsoo, Li, Jian-Liang, Yao, Hang, Brill, Laurence M., Han, Jaeseok, Lau, Eric, Bowtell, David, Haddad, Gabriel, Kaufman, Randal J., Ronai, Ze'ev A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014425/
https://ncbi.nlm.nih.gov/pubmed/24809345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004348
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