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Orthopaedic Wear Particle-induced Bone Loss and Exogenous Macrophage Infiltration is mitigated by Local Infusion of NF-κB Decoy Oligodeoxynucleotide
Excessive production of wear particles from total joint replacements (TJRs) induces chronic inflammation, macrophage infiltration, and consequent bone loss (periprosthetic osteolysis). This inflammation and bone remodeling are critically regulated by the transcription factor NF-κB. We previously dem...
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| Yayımlandı: | J Biomed Mater Res A |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748269/ https://ncbi.nlm.nih.gov/pubmed/28782280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36169 |
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