Interleukin-4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover

Periprosthetic osteolysis remains as a major complication of total joint replacement surgery. Modulation of macrophage polarization with interleukin-4 (IL-4) has emerged as an effective means to limit wear particle-induced osteolysis. The aim of this study was to evaluate the efficacy of local IL-4...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Pajarinen, Jukka, Lin, Tzuhua, Nabeshima, Akira, Sato, Taishi, Gibon, Emmanuel, Jämsen, Eemeli, Khan, Tahsin N., Yao, Zhenyu, Goodman, Stuart B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213865/
https://ncbi.nlm.nih.gov/pubmed/33340244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.37142
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