Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies

The ATP-dependent 90 kDa heat shock protein, Hsp90, is a major regulator of protein triage, from assisting in nascent protein folding to refolding or degrading aberrant proteins. Tau, a microtubule associated protein, aberrantly accumulates in Alzheimer's disease (AD) and other neurodegenerativ...

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Bibliografski detalji
Izdano u:Front Neurosci
Glavni autori: Shelton, Lindsey B., Koren, John, Blair, Laura J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744016/
https://ncbi.nlm.nih.gov/pubmed/29311797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00724
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