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Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies
The ATP-dependent 90 kDa heat shock protein, Hsp90, is a major regulator of protein triage, from assisting in nascent protein folding to refolding or degrading aberrant proteins. Tau, a microtubule associated protein, aberrantly accumulates in Alzheimer's disease (AD) and other neurodegenerativ...
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| Publicado no: | Front Neurosci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5744016/ https://ncbi.nlm.nih.gov/pubmed/29311797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00724 |
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