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CUCURBITACIN D IS A DISRUPTOR OF THE HSP90 CHAPERONE MACHINERY
Heat shock protein 90 (Hsp90) facilitates the maturation of many newly synthesized and unfolded proteins (clients) via the Hsp90 chaperone cycle, in which Hsp90 forms a heteroprotein complex and relies upon co-chaperones, immunophilins, etc. for assistance in client folding. Hsp90 inhibition has eme...
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| Udgivet i: | J Nat Prod |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892428/ https://ncbi.nlm.nih.gov/pubmed/25756299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.5b00054 |
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