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Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres

Telomerase maintains genome integrity by adding repetitive DNA sequences to the chromosome ends in actively dividing cells, including 90% of all cancer cells. Recruitment of human telomerase to telomeres occurs during S-phase of the cell cycle, but the molecular mechanism of the process is only part...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Schmidt, Jens C., Zaug, Arthur J., Cech, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743434/
https://ncbi.nlm.nih.gov/pubmed/27523609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.033
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