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Finding the end: recruitment of telomerase to the telomere

Telomeres, the ends of linear eukaryotic chromosomes, are characterized by the presence of multiple repeats of a short DNA sequence. This telomeric DNA is protected from illicit repair by telomere-associated proteins, which in mammals form the shelterin complex. Replicative polymerases are unable to...

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Bibliografische gegevens
Hoofdauteurs: Nandakumar, Jayakrishnan, Cech, Thomas R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805138/
https://ncbi.nlm.nih.gov/pubmed/23299958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3505
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