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Finding the end: recruitment of telomerase to the telomere
Telomeres, the ends of linear eukaryotic chromosomes, are characterized by the presence of multiple repeats of a short DNA sequence. This telomeric DNA is protected from illicit repair by telomere-associated proteins, which in mammals form the shelterin complex. Replicative polymerases are unable to...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805138/ https://ncbi.nlm.nih.gov/pubmed/23299958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3505 |
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