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Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres

Telomerase maintains genome integrity by adding repetitive DNA sequences to the chromosome ends in actively dividing cells, including 90% of all cancer cells. Recruitment of human telomerase to telomeres occurs during S-phase of the cell cycle, but the molecular mechanism of the process is only part...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Schmidt, Jens C., Zaug, Arthur J., Cech, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743434/
https://ncbi.nlm.nih.gov/pubmed/27523609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.033
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