Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions

Since Huggins defined the androgen-sensitive nature of prostate cancer (PCa), suppression of systemic testosterone (T) has remained the most effective initial therapy for advanced disease although progression inevitably occurs. From the inception of clinical efforts to suppress androgen receptor (AR...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Asıl Yazarlar: Mohammad, Osama S., Nyquist, Michael D., Schweizer, Michael T., Balk, Stephen P., Corey, Eva, Plymate, Stephen, Nelson, Peter S., Mostaghel, Elahe A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742814/
https://ncbi.nlm.nih.gov/pubmed/29210989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9120166
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