Molecular determinants of response to high-dose androgen therapy in prostate cancer

Clinical trials of high-dose androgen (HDA) therapy for prostate cancer (PC) have shown promising efficacy but are limited by lack of criteria to identify likely responders. To elucidate factors that govern the growth-repressive effects of HDAs, we applied an unbiased integrative approach using gene...

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Udgivet i:JCI Insight
Main Authors: Nyquist, Michael D., Corella, Alexandra, Mohamad, Osama, Coleman, Ilsa, Kaipainen, Arja, Kuppers, Daniel A., Lucas, Jared M., Paddison, Patrick J., Plymate, Stephen R., Nelson, Peter S., Mostaghel, Elahe A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795499/
https://ncbi.nlm.nih.gov/pubmed/31503550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129715
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