Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

Androgen receptor (AR) signaling is a distinctive feature of prostate carcinoma (PC) and represents the major therapeutic target for treating metastatic prostate cancer (mPC). Though highly effective, AR antagonism can produce tumors that bypass a functional requirement for AR, often through neuroen...

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Vydáno v:Cancer Cell
Hlavní autoři: Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F., Kaipainen, Arja, Corella, Alexandra N., Yang, Yu Chi, Nyquist, Michael D., Mostaghel, Elahe, Hsieh, Andrew C., Zhang, Xiaotun, Corey, Eva, Brown, Lisha G., Nguyen, Holly M., Pienta, Kenneth, Ittmann, Michael, Schweizer, Michael, True, Lawrence D., Wise, David, Rennie, Paul S., Vessella, Robert L., Morrissey, Colm, Nelson, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750052/
https://ncbi.nlm.nih.gov/pubmed/29017058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.09.003
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