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Exploiting AR Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155

Androgen receptor (AR) signaling is fundamental to prostate cancer and is the dominant therapeutic target in metastatic disease. However, stringent androgen deprivation therapy (ADT) regimens decrease quality of life and have been largely unsuccessful in curtailing mortality. Recent clinical and pre...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Nyquist, Michael D, Corella, Alexandra, Burns, John, Coleman, Ilsa, Gao, Shuai, Tharakan, Robin, Riggan, Luke, Cai, Changmeng, Corey, Eva, Nelson, Peter S, Mostaghel, Elahe A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471626/
https://ncbi.nlm.nih.gov/pubmed/28465296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0315
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