Exploiting AR Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155

Androgen receptor (AR) signaling is fundamental to prostate cancer and is the dominant therapeutic target in metastatic disease. However, stringent androgen deprivation therapy (ADT) regimens decrease quality of life and have been largely unsuccessful in curtailing mortality. Recent clinical and pre...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Cancer Res
Autores principales: Nyquist, Michael D, Corella, Alexandra, Burns, John, Coleman, Ilsa, Gao, Shuai, Tharakan, Robin, Riggan, Luke, Cai, Changmeng, Corey, Eva, Nelson, Peter S, Mostaghel, Elahe A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471626/
https://ncbi.nlm.nih.gov/pubmed/28465296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0315
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares