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Inhibition of survivin with YM155 induces durable tumor response in anaplastic thyroid cancer

PURPOSE: Anaplastic thyroid cancer (ATC) is a rare but lethal malignancy without any effective therapy. The aim of the present study was to use a high-throughput drug library screening to identify a novel therapeutic agent that targets dysregulated genes/pathways in ATC. EXPERIMENTAL DESIGN: We perf...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Mehta, Amit, Zhang, Lisa, Boufraqech, Myriem, Liu-Chittenden, Yi, Zhang, Yaqin, Patel, Dhaval, Davis, Sean, Rosenberg, Avi, Ylaya, Kris, Aufforth, Rachel, Li, Zhuyin, Shen, Min, Kebebew, Electron
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573822/
https://ncbi.nlm.nih.gov/pubmed/25944801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3251
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