Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions

Since Huggins defined the androgen-sensitive nature of prostate cancer (PCa), suppression of systemic testosterone (T) has remained the most effective initial therapy for advanced disease although progression inevitably occurs. From the inception of clinical efforts to suppress androgen receptor (AR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: Mohammad, Osama S., Nyquist, Michael D., Schweizer, Michael T., Balk, Stephen P., Corey, Eva, Plymate, Stephen, Nelson, Peter S., Mostaghel, Elahe A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2017
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742814/
https://ncbi.nlm.nih.gov/pubmed/29210989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9120166
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