Lanean...

Pd-mediated Arylation of Lysine in Unprotected Peptides

A mild method for the arylation of lysine in an unprotected peptide is presented. In the presence of a preformed biarylphosphine-supported Pd(II)-aryl complex and weak base, lysine amino groups underwent C–N bond formation at room temperature. The process generally exhibited high selectivity for lys...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Lee, Hong Geun, Lautrette, Guillaume, Pentelute, Bradley L., Buchwald, Stephen L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741856/
https://ncbi.nlm.nih.gov/pubmed/28206688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611202
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