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Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides

[Image: see text] On the basis of mechanism-driven reaction design, a Pd-catalyzed nucleophilic fluorination of aryl bromides and iodides has been developed. The method exhibits a broad substrate scope, especially with respect to nitrogen-containing heteroaryl bromides, and proceeds with minimal for...

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Autors principals: Lee, Hong Geun, Milner, Phillip J., Buchwald, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954505/
https://ncbi.nlm.nih.gov/pubmed/24559304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5009739
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