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Mild Pd-Catalyzed Aminocarbonylation of (Hetero)Aryl Bromides with a Palladacycle Precatalyst

[Image: see text] A palladacyclic precatalyst is employed to cleanly generate a highly active XantPhos-ligated Pd-catalyst. Its use in low temperature aminocarbonylations of (hetero)aryl bromides provides access to a range of challenging products in good to excellent yields with low catalyst loading...

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Detalhes bibliográficos
Main Authors: Friis, Stig D., Skrydstrup, Troels, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136692/
https://ncbi.nlm.nih.gov/pubmed/25090373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502014b
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