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Mild and Highly Selective Palladium-Catalyzed Monoarylation of Ammonia Enabled by the Use of Bulky Biarylphosphine Ligands and Palladacycle Precatalysts

[Image: see text] A method for the palladium-catalyzed arylation of ammonia with a wide range of aryl and heteroaryl halides, including challenging five-membered heterocyclic substrates, is described. Excellent selectivity for monoarylation of ammonia to primary arylamines was achieved under mild co...

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Detalhes bibliográficos
Main Authors: Cheung, Chi Wai, Surry, David S., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779515/
https://ncbi.nlm.nih.gov/pubmed/23815096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401612c
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