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A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides

[Image: see text] A new biaryl monophosphine ligand (AlPhos, L1) allows for the room-temperature Pd-catalyzed fluorination of a variety of activated (hetero)aryl triflates. Furthermore, aryl triflates and bromides that are prone to give mixtures of regioisomeric aryl fluorides with Pd-catalysis can...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Sather, Aaron C., Lee, Hong Geun, De La Rosa, Valentina Y., Yang, Yang, Müller, Peter, Buchwald, Stephen L.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2015
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721526/
https://ncbi.nlm.nih.gov/pubmed/26413908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b09308
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