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In-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides

[Image: see text] A thorough investigation of the challenging Pd-catalyzed fluorination of five-membered heteroaryl bromides is presented. Crystallographic studies and density functional theory (DFT) calculations suggest that the challenging step of this transformation is C–F reductive elimination o...

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Detalhes bibliográficos
Publicado no:Organometallics
Main Authors: Milner, Phillip J., Yang, Yang, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820280/
https://ncbi.nlm.nih.gov/pubmed/27056379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.organomet.5b00631
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