Caricamento...
Nitrogen Arylation for Macrocyclization of Unprotected Peptides
We describe an efficient and mild method for the synthesis of macrocyclic peptides via nitrogen arylation from unprotected precursors. Various electro-philes and lysine-based nucleophiles were investigated and showed high-yielding product formation, even for a macrocyclization scan with 14 variants....
Salvato in:
| Pubblicato in: | J Am Chem Soc |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6150454/ https://ncbi.nlm.nih.gov/pubmed/27332147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03757 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|