טוען...
Nitrogen Arylation for Macrocyclization of Unprotected Peptides
We describe an efficient and mild method for the synthesis of macrocyclic peptides via nitrogen arylation from unprotected precursors. Various electro-philes and lysine-based nucleophiles were investigated and showed high-yielding product formation, even for a macrocyclization scan with 14 variants....
שמור ב:
| הוצא לאור ב: | J Am Chem Soc |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6150454/ https://ncbi.nlm.nih.gov/pubmed/27332147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03757 |
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