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Pd-mediated Arylation of Lysine in Unprotected Peptides
A mild method for the arylation of lysine in an unprotected peptide is presented. In the presence of a preformed biarylphosphine-supported Pd(II)-aryl complex and weak base, lysine amino groups underwent C–N bond formation at room temperature. The process generally exhibited high selectivity for lys...
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| I publikationen: | Angew Chem Int Ed Engl |
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| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741856/ https://ncbi.nlm.nih.gov/pubmed/28206688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611202 |
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