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ABIN-1 Regulates RIPK1 Activation by Bridging M1 ubiquitination with K63 Deubiquitination in TNF-RSC
Ubiquitination of TNFR1-signaling-complex (TNF-RSC) controls the activation of RIPK1, a kinase critically involved in mediating multiple TNFα activated deleterious events. However, the molecular mechanism that coordinates different types of ubiquitination modifications to regulate the activation of...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741489/ https://ncbi.nlm.nih.gov/pubmed/29203883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-017-0003-1 |
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