ABIN-1 Regulates RIPK1 Activation by Bridging M1 ubiquitination with K63 Deubiquitination in TNF-RSC

Ubiquitination of TNFR1-signaling-complex (TNF-RSC) controls the activation of RIPK1, a kinase critically involved in mediating multiple TNFα activated deleterious events. However, the molecular mechanism that coordinates different types of ubiquitination modifications to regulate the activation of...

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Dziedzic, Slawomir A., Su, Zhenyi, Barrett, Vica Jean, Najafov, Ayaz, Mookhitiar, Adnan K., Amin, Palak, Pan, Heling, Sun, Li, Zhu, Hong, Ma, Averil, Abbott, Derek W., Yuan, Junying
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741489/
https://ncbi.nlm.nih.gov/pubmed/29203883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-017-0003-1
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