Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Stimulation of cells with TNFα can promote distinct cell death pathways, including RIPK1-independent apoptosis, necroptosis, and RIPK1-dependent apoptosis (RDA)—the latter of which we still know little about. Here we show that RDA involves the rapid formation of a distinct detergent-insoluble, highl...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Amin, Palak, Florez, Marcus, Najafov, Ayaz, Pan, Heling, Geng, Jiefei, Ofengeim, Dimitry, Dziedzic, Slawomir A., Wang, Huibing, Barrett, Vica Jean, Ito, Yasushi, LaVoie, Matthew J., Yuan, Junying
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
Ábhair:
PNAS Plus
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042106/
https://ncbi.nlm.nih.gov/pubmed/29891719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806973115
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