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EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo

Despite a well-established role for the epidermal growth factor receptor (EGFR) in tumorigenesis, EGFR activities and endocytosis in tumors in vivo have not been studied. We labeled endogenous EGFR with GFP by genome-editing of human oral squamous cell carcinoma cells, which were used to examine EGF...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Pinilla-Macua, Itziar, Grassart, Alexandre, Duvvuri, Umamaheswar, Watkins, Simon C, Sorkin, Alexander
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741375/
https://ncbi.nlm.nih.gov/pubmed/29268862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31993
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