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EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo
Despite a well-established role for the epidermal growth factor receptor (EGFR) in tumorigenesis, EGFR activities and endocytosis in tumors in vivo have not been studied. We labeled endogenous EGFR with GFP by genome-editing of human oral squamous cell carcinoma cells, which were used to examine EGF...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741375/ https://ncbi.nlm.nih.gov/pubmed/29268862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31993 |
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