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EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo

Despite a well-established role for the epidermal growth factor receptor (EGFR) in tumorigenesis, EGFR activities and endocytosis in tumors in vivo have not been studied. We labeled endogenous EGFR with GFP by genome-editing of human oral squamous cell carcinoma cells, which were used to examine EGF...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Pinilla-Macua, Itziar, Grassart, Alexandre, Duvvuri, Umamaheswar, Watkins, Simon C, Sorkin, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741375/
https://ncbi.nlm.nih.gov/pubmed/29268862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31993
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