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Quantitative Analysis of Endocytosis and Turnover of Epidermal Growth Factor (EGF) and EGF Receptor

Binding of epidermal growth factor (EGF) to the EGF receptor (EGFR) initiates signal transduction, ultimately leading to altered gene expression. Ligand-activated EGFR is also rapidly internalized and then targeted to lysosomes for degradation or recycled back to the plasma membrane. Endocytosis is...

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Detaylı Bibliyografya
Asıl Yazarlar: Sorkin, Alexander, Duex, Jason E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878126/
https://ncbi.nlm.nih.gov/pubmed/20235100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb1514s46
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