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Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

Endocytosis of the epidermal growth factor receptor (EGFR) is important for the regulation of EGFR signaling. However, EGFR endocytosis mechanisms are poorly understood, which precludes development of approaches to specifically inhibit EGFR endocytosis and analyze its impact on signaling. Using a co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goh, Lai Kuan, Huang, Fangtian, Kim, Woong, Gygi, Steven, Sorkin, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878939/
https://ncbi.nlm.nih.gov/pubmed/20513767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001008
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