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Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

Endocytosis of the epidermal growth factor receptor (EGFR) is important for the regulation of EGFR signaling. However, EGFR endocytosis mechanisms are poorly understood, which precludes development of approaches to specifically inhibit EGFR endocytosis and analyze its impact on signaling. Using a co...

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Bibliografiske detaljer
Main Authors: Goh, Lai Kuan, Huang, Fangtian, Kim, Woong, Gygi, Steven, Sorkin, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878939/
https://ncbi.nlm.nih.gov/pubmed/20513767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001008
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