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Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

Endocytosis of the epidermal growth factor receptor (EGFR) is important for the regulation of EGFR signaling. However, EGFR endocytosis mechanisms are poorly understood, which precludes development of approaches to specifically inhibit EGFR endocytosis and analyze its impact on signaling. Using a co...

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Detalhes bibliográficos
Main Authors: Goh, Lai Kuan, Huang, Fangtian, Kim, Woong, Gygi, Steven, Sorkin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878939/
https://ncbi.nlm.nih.gov/pubmed/20513767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001008
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