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Endocytosis and intracellular trafficking of ErbBs

This review article describes the pathways and mechanisms of endocytosis and post-endocytic sorting of the EGF receptor (EGFR/ErbB1) and other members of the ErbB family. Growth factor binding to EGFR accelerates its internalization through clathrin-coated pits which is followed by the efficient lys...

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Detalhes bibliográficos
Main Authors: Sorkin, Alexander, Goh, Lai Kuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605728/
https://ncbi.nlm.nih.gov/pubmed/18793634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.07.029
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