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Endocytosis of Receptor Tyrosine Kinases

Endocytosis is the major regulator of signaling from receptor tyrosine kinases (RTKs). The canonical model of RTK endocytosis involves rapid internalization of an RTK activated by ligand binding at the cell surface and subsequent sorting of internalized ligand-RTK complexes to lysosomes for degradat...

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Detalles Bibliográficos
Main Authors: Goh, Lai Kuan, Sorkin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632065/
https://ncbi.nlm.nih.gov/pubmed/23637288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017459
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