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Endocytosis of Receptor Tyrosine Kinases
Endocytosis is the major regulator of signaling from receptor tyrosine kinases (RTKs). The canonical model of RTK endocytosis involves rapid internalization of an RTK activated by ligand binding at the cell surface and subsequent sorting of internalized ligand-RTK complexes to lysosomes for degradat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632065/ https://ncbi.nlm.nih.gov/pubmed/23637288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017459 |
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