Llwytho...
Reduction of nonspecificity motifs in synthetic antibody libraries
Successful antibody development requires both functional binding and desirable biophysical characteristics. In the current study we analyze the causes of one hurdle to clinical development, off-target reactivity or nonspecificity. We used a high-throughput nonspecificity assay to isolate panels of n...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Mol Biol |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2017
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5738262/ https://ncbi.nlm.nih.gov/pubmed/29183788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.11.008 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|