Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs.

Construction of synthetic combinatorial libraries is described that allows for the generation of a library of motifs rather than a library of compounds. Peptide libraries based on this strategy were synthesized and screened with model targets streptavidin and anti-beta-endorphin antibody. The screen...

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Detaylı Bibliyografya
Asıl Yazarlar: Sepetov, N F, Krchnák, V, Stanková, M, Wade, S, Lam, K S, Lebl, M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC41707/
https://ncbi.nlm.nih.gov/pubmed/7777524
Etiketler: Etiketle
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