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Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs.

Construction of synthetic combinatorial libraries is described that allows for the generation of a library of motifs rather than a library of compounds. Peptide libraries based on this strategy were synthesized and screened with model targets streptavidin and anti-beta-endorphin antibody. The screen...

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Dettagli Bibliografici
Autori principali: Sepetov, N F, Krchnák, V, Stanková, M, Wade, S, Lam, K S, Lebl, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC41707/
https://ncbi.nlm.nih.gov/pubmed/7777524
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