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Synthetic molecular evolution of pore–forming peptides by Iterative combinatorial library screening
We previously reported the de novo design of a combinatorial peptide library that was subjected to high–throughput screening to identify membrane permeabilizing antimicrobial peptides that have β–sheet–like secondary structure. Those peptides do not form discreet pores in membranes but instead parti...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644507/ https://ncbi.nlm.nih.gov/pubmed/23394375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300598k |
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