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Conformational Fine-Tuning of Pore-Forming Peptide Potency and Selectivity
[Image: see text] To better understand the sequence–structure–function relationships that control the activity and selectivity of membrane-permeabilizing peptides, we screened a peptide library, based on the archetypal pore-former melittin, for loss-of-function variants. This was accomplished by ass...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697923/ https://ncbi.nlm.nih.gov/pubmed/26632653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b10595 |
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