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Rational screening of oligonucleotide combinatorial libraries for drug discovery.

Combinatorial strategies offer the potential to generate and screen extremely large numbers of compounds and to identify individual molecules with a desired binding specificity or pharmacological activity. We describe a combinatorial strategy for oligonucleotides in which the library is generated an...

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Detalhes bibliográficos
Main Authors: Ecker, D J, Vickers, T A, Hanecak, R, Driver, V, Anderson, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC309424/
https://ncbi.nlm.nih.gov/pubmed/7684128
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