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Generation and screening of an oligonucleotide-encoded synthetic peptide library.

We have prepared a library of approximately 10(6) different peptide sequences on small, spherical (10-microns diameter) beads by the combinatorial chemical coupling of both L- and D-amino acid building blocks. To each bead is covalently attached many copies of a single peptide sequence and, addition...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Needels, M C, Jones, D G, Tate, E H, Heinkel, G L, Kochersperger, L M, Dower, W J, Barrett, R W, Gallop, M A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47845/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10700
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