Generation and screening of an oligonucleotide-encoded synthetic peptide library.

We have prepared a library of approximately 10(6) different peptide sequences on small, spherical (10-microns diameter) beads by the combinatorial chemical coupling of both L- and D-amino acid building blocks. To each bead is covalently attached many copies of a single peptide sequence and, addition...

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Bibliographic Details
Main Authors: Needels, M C, Jones, D G, Tate, E H, Heinkel, G L, Kochersperger, L M, Dower, W J, Barrett, R W, Gallop, M A
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47845/
https://ncbi.nlm.nih.gov/pubmed/7504279
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