High affinity type I interleukin 1 receptor antagonists discovered by screening recombinant peptide libraries.

Two families of peptides that specifically bind the extracellular domain of the human type I interleukin I (IL-1) receptor were identified from recombinant peptide display libraries. Peptides from one of these families blocked binding of IL-lalpha to the type I IL-1 receptor with IC50 values of 45-1...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Yanofsky, S D, Baldwin, D N, Butler, J H, Holden, F R, Jacobs, J W, Balasubramanian, P, Chinn, J P, Cwirla, S E, Peters-Bhatt, E, Whitehorn, E A, Tate, E H, Akeson, A, Bowlin, T L, Dower, W J, Barrett, R W
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1996
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8693002/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7381
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